TURKISH JOURNAL OF ONCOLOGY 2012 , Vol 27 , Num 2
Insufficiency fractures following pelvic radiotherapy of gynecologic malignancies
Sevim ÖZDEMİR,1 Beyza AYKUT,2 Eda ÖZER,1 Arzu ERGEN,1 Fatih KANTARCI,2 İsmet ŞAHİNLER1
1İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul
2İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Radyoloji Anabilim Dalı, İstanbul
OBJECTIVES
In this article, insufficiency fractures (IF) after pelvic radiotherapy were examined.

METHODS
We studied nine gynecologic malignancy patients who underwent pelvic radiotherapy. Patients' ages, menopausal status, external pelvic radiotherapy dose, IF localization area and development time, treatment, and treatment response time were investigated.

RESULTS
The mean age was 54 years. Five patients were postmenopausal, and five patients had osteoporosis. The mean follow-up and development period of IF were 49 and 26.8 months, respectively. The IF field was located in the sacrum in 8 patients and the sacroiliac joint in 1 patient. Pelvic pain was the initial complaint in 8 patients. One patient was asymptomatic. IF formation time ranged from 6-156 months. After symptomatic medical therapy and resting, the visual analogue scale (VAS) score decreased from 7 initially to 2. Treatment response time was 3.4 months.

CONCLUSION
IF should be considered as a late complication of external radiotherapy in patients experiencing pelvic pain after pelvic radiotherapy. Keywords : External pelvic radiotherapy; gynecologic malignancy; pelvic pain