TURKISH JOURNAL OF ONCOLOGY 2015 , Vol 30 , Num 1
Clinical features of Hodgkin's lymphoma patients and retrospective analysis of treatment results: a single center experience
Yahyahan MEMİŞ, Mustafa KANDAZ, Lasif SERDAR, Özlem AYNACI, Aslı ŞAHBAZ, Gülşen SOYDEMİR, Zümrüt BAHAT, Emine CANYILMAZ, Adnan YÖNEY
Karadeniz Teknik Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, Trabzon OBJECTIVES
Study clinical features and treatment results of patients with Hodgkin's lymphoma and investigate prognostic factors affecting survival.

METHODS
Data of 92 Hodgkin's lymphoma patients treated and monitored at our center between 1996 and 2013 was studied retrospectively.

RESULTS
73% of the patients had early stage (stage I-II) and 27% of the patients had late stage (stage III-IV) of the disease. The most common histological types were nodular sclerosis Hodgkin's lymphoma (47%) and mixed cellular Hodgkin's lymphoma (MCHL) (35%). Median survival time was 193.08±15.41 months and 1-, 3-, 5- and 10-year survival rates were 97.7%, 87.1%, 80.4% and 72.9% respectively. In univariate analysis, stage (p<0.0001), bulky disease (p<0.025), presence of risk factors (p<0.0001) and recurrence (p<0.027) were found to be variables with effects on overall survival.

CONCLUSION
Median survival time and survival rates of our study are compatible with those of other studies in the literatüre. Keywords : Stage; Hodgkin's lymphoma; survival; prognostic factors