TURKISH JOURNAL OF ONCOLOGY 2015 , Vol 30 , Num 3
Definition of the set-up error using 2D radiographic images and 3D computed tomography and dosimetric effect of set-up errors for head and neck/lung radiotherapy patients
Cemile CEYLAN, Abdülkadir ARSLAN, Barış KAFKAS, Yücel ÇEKİÇKESEN, Figen MOLLAOĞLU, Abidin TECİK, Nurşad KORKMAZ, Hande AYATA, Ayhan KILIÇ, Timur UĞUR, Metin GÜDEN, Kayıhan ENGİN
Anadolu Sağlık Merkezi, Radyasyon Onkolojisi Kliniği, Kocaeli OBJECTIVES
In this study, the comparison of the set-up accuracy using twodimensional kilo voltage (kV-kV) imaging and three-dimensional cone beam CT (CBCT) in head and neck/lung radiotherapy patients was done.

METHODS
404 images of all 8 head and neck and 9 lung patients studied to find 2D and 3D set-up errors. CTV to PTV margins were obtained using calculated set-up errors. The plans of the selected head and neck and lung patients were calculated to investigate dosimetric effect of the set-up errors.

RESULTS
kV-kV and CBCT detected average set-up errors for head and neck patients were less than 2 mm. kV-kV and CBCT detected average set-up errors for lung patients were less than 7 mm. While there was a statistically differences (p<0.05) for lung patients, no statistically differences was found for head and neck cases as compared kV-kV and CBCT image data sets. The calculated margin using CBCT image data sets was found bigger than the calculated margin using kV-kV image data sets. The adequate and clinically accepted margins were calculated for both IGRT approach. The neglible dosimetric effects were observed for both data sets.

CONCLUSION
We conclude that the 2D radiographic image of head and neck radiotherapy patient reduces positioning errors. While 3D registration of CBCT and planning CT of head and neck cases adds little improvement comparing with 2D images, 3D CBCT images of lung radiotherapy patients provided more accurate information of the set-up errors. Keywords : Set-up; CBCT; kV-kV