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¹Department of Medical Oncology, İstanbul Bilim University Faculty of Medicine, İstanbul-Turkey
²Department of Internal Medicine, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul-Turkey
³Department of Internal Medicine, Bağcılar Training and Research Hospital, İstanbul-Turkey While multiple primary tumors are rarely reported in literature, we expect that it will be seen more often in the future as a result of improvements in diagnosis and treatment of cancer. Molecular targeted therapies are promising modalities that are now used more commonly. Presently described is oncological response for a 70-year-old women with multiple primary cancers - breast and lung - in which 2 targeted therapies were administered. While there is currently no standard therapy in the literature for multiple primary cancers, it is the authors' suggestion that targeted therapies may be a promising choice for these cases. Keywords : Invasive ductal carcinoma; lung adenocarcinoma; multiple primary cancer; targeted therapies