Impact of Peritumoral Edema on Overall Survival in Glioblastoma Multiforme
The aim of the present study was to investigate the relationship between peritumoral edema and overall
survival in glioblastoma multiforme (GBM).
Total of 101 patients with radiologically or pathologically GBM were included in this study. Data of
patient age, sex, tumor dimensions, and preoperative peritumoral edema were analyzed.
While average survival was 16.67±3.99 months (95% confidence interval [CI]: 8.85-24.49 months)
and 1- and 3-year survival rates were 50% and 16.7%, respectively, for patients without edema, average
survival was 13.74±1.95 months (95% CI: 9.91-17.58 months) and 1- and 3-year survival rates were
35.6% and 8.5%, respectively, for patients with edema. No statistical difference between them was found
Prognostic value of edema for survival could not be determined in this retrospective analysis of homogeneous
group of patients with isolated GBM.