TURKISH JOURNAL OF ONCOLOGY 2017 , Vol 1 , Num 3
Hydrogel Spacer may Allow Prostate Re-irradiation even in Patients with Ulcerative Colitis: A Case Report
Mariangela MASSACCESI1,Luca TAGLIAFERRI1,Lucia CERVONE2,Antonio PIRAS2,Sebastiano MENNA1,Luigi AZARİO1,Gian Carlo MATTIUCCI1,Patrizia CORNACCHIONE1,Valentina LANCELLOTTA1,Maria ANTONIETTA GAMBACORTA1,Vincenzo VALENTINI1
1Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome-Italy
2Università Cattolica del Sacro Cuore, Rome-Italy
DOI : 10.5505/tjo.2019.2057 Salvage radiotherapy is a valid option for locally recurrent prostate cancer (PC) patients. Two of the treatment options are as follows: interventional radiotherapy or stereotactic body radiotherapy (SBRT). SBRT has the main advantage as a noninvasive procedure. Synthetic gel injection into the prostate and rectum space, as a novel technique in prostate radiotherapy, spares the anterior rectal wall from a high dose. Inflammatory bowel disease, including Crohn"s disease and ulcerative colitis (UC), contraindicate external beam radiotherapy due to increased bowel complication risk. In this study, we describe the first PC patient with UC in remission treated with salvage SBRT and hydrogel rectal spacer. After ten months of follow-up, no bowel symptoms were reported, and SBRT provided both biochemical and clinical response. Even patients with UC and radio-recurrent PC may be viable salvage SBRT candidates. Keywords : Hydrogel rectal spacer; recurrent prostate cancer; re-irradiation; stereotactic radiotherapy