TURKISH JOURNAL OF ONCOLOGY 2013 , Vol 28 , Num 2
Thymic tumors and outcomes after radiotherapy
Süreyya SARIHAN,1 Ahmet Sami BAYRAM,2 Cengiz GEBİTEKİN,2 Ömer YERCİ,3 Lütfi ÖZKAN1
1Uludağ Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, Bursa
2Uludağ Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi Anabilim Dalı, Bursa
3Uludağ Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Bursa
OBJECTIVES
We evaluated the results of treatment in patients with thymic tumors treated with postoperative adjuvant radiotherapy.

METHODS
Eighteen patients were treated median 5400 cGy radiotherapy between 1995-2010. Diagnosis of patients were thymoma (n=10), thymic carcinoma (n=7), thymic neuroendocrin carcinoma (n=1). R0 resection was made on 12 of them. According to prognostic stratification with Masaoka stage and WHO classification, there were 5 good, 7 moderate, and 6 poor risk patients. Survival was calculated from diagnosis.

RESULTS
A total of 33% patients were recurred median 29.5 months with 34 months follow-up. Local control, median overall and disease-free survival for all patients were 77%, 113 months, and 105 months. Local control for good, moderate, poor risk groups were found 100%, 71%, 50%. There were significant differences survival rates for Masaoka stage, R0 resection, and prognostic groups.

CONCLUSION
Prognostic risk classification was found to be better predictive in terms of local control and survival. Keywords : Thymic tumor; adjuvant radiotherapy; local control; prognostic group; survival