TURKISH JOURNAL OF ONCOLOGY 2015 , Vol 30 , Num 4
Fdg pet/ct in pediatric Hodgkin's lymphoma
Sabire YILMAZ AKSOY,1 Metin HALAC2
1Ankara Atatürk Eğitim ve Araştırma Hastanesi, Nükleer Tıp Anabilim Dalı, Ankara
2İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Nükleer Tıp Anabilim Dalı, İstanbul
The increased glucose metabolism results increased 18FFluorodeoxyglucose (FDG) accumulation of the malignant cells. Similarly, Hodgkin's lymphoma (HL) show high FDG uptake. Lymphocyte-predominant types of HL demonstrate lower FDG accumulation than classic type HL. PET/CT can detect almost all lesion greater than 0.5–1 cm. Additionally, FDG PET/CT help us in monitoring treatment response by showing glucose metabolism and FDG uptake of the cells after chemotherapy. The sensitivity of FDG PET/CT is higher than other imaging modalities in detecting nodular or diffuse lesions of HL. Also, it has higher sensitivity in showing bone marrow involvement than bone marrow biopsy. As a result, FDG PET/CT is a widely accepted and superior imaging modality in staging, re-staging and evaluating treatment response of pediatric HL. Keywords : FDG PET/CT, pediatric Hodgkin's lymphoma