TURKISH JOURNAL OF ONCOLOGY 2020 , Vol 35 , Num 2
Validation of the EORTC-QLQ-HN35 Questionnaire in Turkish Head and Neck Cancer Patients
Sezin YÜCE SARI1,Çağlayan Selenge BEDÜK ESEN1,Deniz YÜCE2,Mustafa CENGİZ1,Gökhan ÖZYİĞİT1,Gözde YAZICI1
1Department of Radiation Oncology, Hacettepe University Faculty of Medicine, Ankara-Turkey
2Department of Preventive Oncology, Hacettepe University Faculty of Medicine, Ankara-Turkey
DOI : 10.5505/tjo.2019.2195 OBJECTIVE
To assess the validity and reliability of the EORTC-QLQ-HN35 in Turkish head and neck cancer (HNC) patients.

METHODS
EORTC QLQ-C30 and QLQ-HN35 scales were completed by patients at the beginning, middle and end of radiotherapy. Internal consistency was assessed by Cronbach alpha and test-retest reliability by intraclass correlation coefficients (ICCs). Content validity was based on expert opinion and patient reviews.

RESULTS
Eighty patients were included in this study. Mean age was 59±10.7 years. Overall internal consistency was satisfactory (?=0.926). Overall test-retest reliability was satisfactory and ICCs ranged between 0.77 and 0.84. Correlations between corresponding domains of QLQ-C30 and HN35 showed satisfactory convergent validity (r=0.61 to r=0.73). Assessments based on expert opinions and patient reviews also favored the content validity of the scale.

CONCLUSION
The Turkish version of the QLQ-HN35 scale is a valid and reliable tool to evaluate the health-related quality of life in patients with HNC. Keywords : Head and neck cancer; quality of life; questionnaire; radiotherapy; validation