TURKISH JOURNAL OF ONCOLOGY 2017 , Vol 1 , Num 3
Effect of Risk Factors on Local and Systemic Control in Stage 1 Endometrial Cancer
Binnur DÖNMEZ YILMAZ1,Özge KANDEMİR GÜRSEL1
1Department of Radiation Oncology, Prof. Dr. Cemil Taşcıoğlu City Hospital, İstanbul-Turkey DOI : 10.5505/tjo.2020.2431

Summary

OBJECTIVE
This study aims to evaluate the treatment outcomes according to the risk groups of patients with Stage 1 endometrial cancer and to investigate the effects of the risks associated with the disease in the control of the disease.

METHODS
Three hundred and ninety patients who were treated with the indication of endometrial cancer in our clinic were evaluated with the approval of the ethics committee. The data of 114 patients who were evaluated retrospectively between 2014-2018.

RESULTS
In patients with a median age of 58 (35-89) years, histological distribution of pathologies revealed the presence of cases of the 107 endometrioid adenocarcinoma (93%), two serous (1.7%), two clear cells (1.7%), one mucinous (0.8%) carcinomas and two (1.7%) carcinosarcoma. High risk was detected in 14 (12.28%), high to intermediate risk in nine (7%), intermediate risk in 35 (30.7%), and low-risk in 56 p (49%) patients. Recurrence developed in five (4%) patients whose survival was found to be statistically significantly lower than those without recurrence (logrank: 41.74 p=0.0001). Five -year survival rate was 95% and the mean (±SD) survival time was 78.46±1.27 months.

CONCLUSION
In the treatment of Stage 1 endometrial cancer, the survival rates achieved in our disease-recurrence group was statistically significantly lower than those who did not develop recurrences (logrank: 41.74 p=0.0001).