TURKISH JOURNAL OF ONCOLOGY 2017 , Vol 1 , Num 3
Synchronous Burkitt"s Lymphoma of Breast and Colon in a Female Patient: A Report of a Case and Review of Literature
Mohammad Eslami JOUYBARİ1,Anahita NOSRATİ2,Elham Sadat BANİMOSTAFAVİ3,Mohammad Mehdi Ghaffari HAMEDANİ4,Abdolrahim AHMADİ5,Marzieh BATHAEİ2
1Department of Oncology, Gastrointestinal Cancer Research Center, Mazandaran University of Medical Science, Sari-Iran
2Department of Pathology, Imam Khomeini Hospital, Mazandaran University of Medical Science, Sari, Iran
3Department of Radiology, Imam Khomeini Hospital, Mazandaran University Of Medical Science, Sari, Iran
4Department of Surgery, Imam Khomeini Hospital, Mazandaran University of Medical Science, Sari, Iran
5Imam Khomeini Hospital, Mazandaran University of Medical science, Amol, Iran
6Gastrointestinal Cancer Research Center, Mazandaran University of Medical science, Sari, Iran
DOI : 10.5505/tjo.2020.2208

Summary

Burkitt"s lymphoma (BL) is a highly aggressive cancer of B-cells, which is more prevalent in African children. Extranodal involvement of the BL is not a common entity. Herein, we report a young woman who referred to University hospital due to rectorrhagia and breast swelling. Colonoscopy examination revealed a large tumoral lesion of 5×6 cm with superficial ulceration in proximal of ascending colon. Computed tomography (CT) scan of the abdomen showed a 55×42 mm mass in ascending colon and caecum. No lymphadenopathy, splenomegaly and hepatomegaly were reported. Breast ultrasound was performed showed a 24×11 mm hypoechoic heterogeneous mass in the left breast. Bone marrow biopsy was normal. Immunohistochemical assay of colon and breast biopsies confirmed the diagnosis of primary BL. After four courses of chemotherapy, PET-CT revealed complete remission and no sign of metastasis. Since BL is a rapidly-growing neoplasm, prompt diagnosis and treatment can prevent unnecessary surgery and consequences of delay in treatment.