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Ondokuzmayıs Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları AD General information was given reletad to 5-nucleotidase that was a plasma membran ectoenzym. This enzyme raises to more specific according to serum alkalin phosphatase in various liver diseases. Changes in this enzyme levels at the various leucemic patients and literature related to this Subject were reviewed. Keywords :