TURKISH JOURNAL OF ONCOLOGY 2019 , Vol 34 , Num 1
Interventional Oncology: Should Interventional Radiotherapy (Brachytherapy) be Integrated into Modern Treatment Procedures?
György KOVÁCS1,2,Luca TAGLİAFERRİ3,4,Valentina LANCELLOTTA3,7,Attila KOVÁCS5,Roberto IEZZİ3,6,8,Maria-Antonetta GAMBACORTA3,7,9
1Interdisciplinary Brachytherapy Unit, University of Lübeck/UKSH-CL, Lübeck-Germany
2Gemelli-INTERACTS Educational Program Director, Rome-Italy
3Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome-Italy
4Gemelli-INTERACTS Course Teacher and Local Organizer, Rome-Italy
5Department of Diagnostic and Interventional Radiology and Neuroradiology, Medi Clin Robert Janker Klinik, Bonn-Germany
6Department of Radiological Sciences, Radiotherapy and Hematology, Institutodi Radiologia, Policlinico A. Gemelli, Rome-Italy
7Gemelli-INTERACTS Courses Teacher, Rome-Italy
8Università Cattolica del Sacro Cuore, Rome-Italy
DOI : 10.5505/tjo.2019.4 OBJECTIVE
The delivery of a very high dose by radiotherapy to a dedicated target with minimal surrounding normal tissue dose is a challenging situation. From a radiotherapy point of view, in several anatomic situations, the most optimal method is the use of interventional radiotherapy (brachytherapy; IRT) alone or in combination with other established interventional tumor cell eliminating methods.

METHODS
First, Interventional Radiotherapy, Interventional Radiology, Interventional Endoscopy and Interventional Chemotherapy have the same aim of eliminating tumor tissue. Second, target definition and some IRT application techniques need multidisciplinary teamwork.

RESULTS
Multidisciplinary teams have the best potential to offer the best possible cure in localized solid tumors or in selected oligometastatic disease. Examples for this kind of service are given for H&N-, anal-, vaginal-, breast-, prostate cancers as well as in oligometastatic disease. The combined use of interventional tumor ablation techniques is demonstrated.

CONCLUSION
Interventional Oncology has the potential to improve the treatment results in localized solid cancers or in selected oligometastatic disease, and large workload Interventional Oncology Centers could have an important role in the patient service, in the education as well as in the clinical research. Keywords : Brachytherapy; interventional oncology; interventional radiotherapy; multidisciplinarity; personalized medicine; world-class medicine