TURKISH JOURNAL OF ONCOLOGY 2021 , Vol 36 , Num 1
Relation between Histopathology of Head and Neck Cancers and FDG-PET/CT Parameters
Suat BİLİCİ1,Cihan GÜNDOĞAN2,Ahmet Volkan SÜNTER3,Esra MİSİR3,Özgür YİĞİT3
1Department of Otorhinolaryngology and Head Neck Surgery, Acıbadem University,Acıbadem Atakent Hospital, İstanbul-Turkey
2Department of Nuclear Medicine, İstanbul Training and Research Hospital, İstanbul-Turkey
3Department of Otorhinolaryngology and Head Neck Surgery, İstanbul Training and Research Hospital, İstanbul-Turkey
DOI : 10.5505/tjo.2020.2448 OBJECTIVE
To analyse the relationship between histology of head and neck cancers and maximum standardized uptake value (SUVmax) and metabolic tumor volume (MTV).

METHODS
Positron-emission tomography (PET)/computed tomography (CT) examinations of patients with head and neck squamous cell carcinoma (SCC) and non-squamous cell carcinoma (non-SCC) tumors with 52 patients reviewed from 2007 to 2019 retrospectively. MTV and SUVmax values of primary tumor were measured in PET/CT and both groups were statistically compared.

RESULTS
The median SUVmax value was 17.88 (3?52) and MTV was 5.40 (0-329). No significant difference was established between the groups in terms of age, gender and MTV (p=0.948, p=0.166 and p=0.189) respectively. SUVmax value in SCC group was significantly higher (p=0.003) than the non-SCC group.

CONCLUSION
Head and neck squamous cell carcinomas (HNSCC) have higher SUVmax values than non SCC tumors. No significant difference was established between the groups in terms of MTV. Keywords : Head and neck cancer; metabolic tumor volume; positron emission tomography; squamous cell carcinoma; standardized uptake value