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¹İ.Ü. Cerrahpaşa Tıp Fakültesi, Çocuk Hematoloji Onkoloji Bilim Dalı, İstanbul
²İ.Ü. Cerrahpaşa Tıp Fakültesi, Radyoloji Anabilim Dalı, İstanbul Neuroblastoma is the most common extracranial solid tumour in childhood. Neuroblastoma is sometimes seen with neurofibromatosis. A one year old boy was investigated for fever, anemia, subcutaneous soft tissue nodules, exophtalmus, horizontal nystagmus, café-au lait spots, hepatosplenomegaly and lymphadenomegaly and was referred to Pediatric Hematology- Oncology clinic. The patient was initially diagnosed as neurofibromatosis and juvenile myelomonocytic leukemia but his final diagnosis was neuroblastoma. Neurofibroma and neuroblastoma both originate from neural crest cells and they share a common pathogenesis. It is important to evaluate children who are diagnosed as neurofibromatosis for neuroblastoma especially when there is a fast growing mass. Radiology and urine catecholamine levels may be helpful in diagnosis. Keywords : Child; juvenile myelomonocytic leukemia; neuroblastoma; neurofibromatosis