TURKISH JOURNAL OF ONCOLOGY 2012 , Vol 27 , Num 3
Medical treatment in childhood metastatic adrenocortical carcinoma: case report
Fatma Betül ÇAKIR,1 Rejin KEBUDİ,2,3 Ömer GÖRGÜN,2,3 Erbuğ KESKİN4
1Bezmialem Vakıf Üniversitesi, Çocuk Hematoloji-Onkoloji Bilim Dalı, İstanbul
2İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Pediatrik Hematoloji-Onkoloji Anabilim Dalı, İstanbul
3Onkoloji Enstitüsü, Pediatrik Hematoloji-Onkoloji Anabilim Dalı, İstanbul
4İstanbul Üniversitesi İstanbul Tıp Fakültesi, Pediatrik Cerrahi Anabilim Dalı, İstanbul
Adrenocortical carcinoma is a rare endocrine tumor in childhood. It is curable when it is resected totally. However, medical therapy is challenging in patients with metastatic disease. Herein, we present the response to various salvage chemotherapy modalities in addition to mitotane therapy, which were administered to a child with progressive and metastatic adrenocortical tumor. The patient has been under follow-up with progressive disease for 17 months. Keywords : Adrenocortical carcinoma; hand-foot syndrome; gemcitabine; capecitabine; paclitaxel; sorafenib