2Selçuk Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, Konya OBJECTIVES
Adult intracranial ependymomas constitute 2-5% of all intracranial tumors. The aim of this study was to evaluate postoperative results and prognostic factors.
METHODS
Twenty-one patients over the age of 18 who received radiotherapy
in our department between 1996 and 2009 were retrospectively
evaluated.
RESULTS
The median progression-free survival time was 110 months.
Two-, five- and 10-year progression-free survival rates were
80%, 66% and 66%, respectively. The median overall survival
time was 124 months. Two-, five- and 10-year overall survival
rates were 92%, 73% and 73%, respectively. The negative
prognostic factors affecting progression and overall survival
were >15 cm3 tumor volume and removal of the mass with
subtotal resection and biopsy.
CONCLUSION
As a result of our study, the prognostic significance of surgical
extension and tumor volume were shown in adult ependymoma
patients. However, our results should be verified by studies
with large numbers of patients.