TURKISH JOURNAL OF ONCOLOGY 2012 , Vol 27 , Num 4
The effect of different calculation algorithms in non-small-cell lung cancer 3-dimensional conformal radiotherapy planning on lung dose-volume parameters
Mehmet Şükrü ADIGÜL, Ayşe Nur DEMİRAL, Zafer KARAGÜLER
Dokuz Eylül Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İzmir OBJECTIVES
It was aimed to compare two different planning algorithms (Pencil Beam and Convolution Superposition) with regard to lung dose-volume parameters obtained from the created 3-D conformal radiotherapy plans of lung cancer patients who had lobectomy/bilobectomy surgery.

METHODS
The treatment plans of 10 lung cancer patients administered adjuvant 3-D conformal radiotherapy were evaluated in this study. Using two different algorithms, calculations were performed for 6 and 18 MV-X photon beams, respectively. The differences on the relevant lung dose-volume parameters were analyzed.

RESULTS
In terms of lung dose-volume parameters, the difference between the algorithms was statistically significant in V5, V13 and V30 obtained from plans for 6 MV-X photon beam energy (p=0.005; p=0.005; p=0.008, respectively).

CONCLUSION
Higher values were found especially in parameters expressing “low dose area of lungs” for Convolution/Superposition algorithm in radiotherapy planning. Convolution/Superposition algorithm should be preferred to Pencil Beam algorithm due to its increased accuracy in dose calculation in radiotherapy planning. Keywords : Convolution/superposition; pencil beam; lung cancer; lung dose-volume parameters