TURKISH JOURNAL OF ONCOLOGY 2017 , Vol 1 , Num 1
Curative Radiotherapy Outcomes in Elderly Bladder Cancer Patients: A Single-Center Experiences
Berrin İNANÇ1,Özlem MERMUT1
1Department of Radiation Oncology, Istanbul Training and Research Hospital, Istanbul-Turkey DOI : 10.5505/tjo.2021.2511

Summary

OBJECTIVE
In this retrospective research, it was aimed to evaluate results of radiotherapy (RT) in elderly bladder cancer patients.

METHODS
A total of 47 patients who receiving RT or chemoradiotherapy treatment for bladder cancer in elderly patient (>70 years) were included in the study.

RESULTS
In total 47 patients, 4 patients (8.5%) had Stage I, 38 patients (80.8%) had Stage II, and 5 patients (10.6%) had Stage III bladder cancer. About 76.9% of patients had invasive urothelial, 3.8% of patients had squamous and micropapillary carcinoma, and 19.2% of had other (adenocarcinoma) histopathological type. Gender, age, family cancer history, hematuria, smoking, bladder carcinoma type, Charlson CoMorbidity Index, RT dose, concurrent chemoradiotherapy, metastasis side, acute and late toxicity, and follow-up duration of patients showed insignificant differences according to stage (p>0.05). We found that overall survival and disease-free survival (DFS) were statistically significant according to the stages (p<0.05). DFS for Karnofsky Performance Status (KPS) >70 group (25.97±19.06) was higher than KPS <70 group (2.37±1.53) with statistically significant difference (p<0.05).

CONCLUSION
Curative RT and chemoradiotherapy can be safe regimen for older (>70 year) patients with bladder cancer. Nonetheless, KPS and geriatric assessments tools should be consideration before RT and chemoradiotherapy administration.