TURKISH JOURNAL OF ONCOLOGY 2022 , Vol 37 , Num 4
Clinical Outcome and Characteristics of Turkish Breast Cancer Patients who had SARS-Cov-2 Infection
Aysun IŞIKLAR1,Rehile ZENGİN2,Veysel BALCI3,Ayşe SESİN KOCAGÖZ2,Gül BAŞARAN4
1Department of Internal Medicine, Acibadem Altunizade Hospital, İstanbul-Türkiye
2Department of Infectious Diseases and Clinical Microbiology, Acibadem Altunizade Hospital, İstanbul-Türkiye
3Department of Emergency, Acibadem Altunizade Hospital, İstanbul-Türkiye
4Department of Internal Medicine and Oncology, Acıbadem University Faculty of Medicine, İstanbul-Türkiye
DOI : 10.5505/tjo.2022.3692 OBJECTIVE
COVID-19 pandemic has placed an unprecedented burden on health-care system. Patients with cancer are reported to have a higher risk of infection and a more complicated COVID-19 course. Breast cancer (BC) is the most common cancer in women in Turkey. We report clinical outcomes and characteristics of patients with COVID-19 who were on treatment for BC at our center.

METHODS
We reviewed medical records of BC patients who had COVID-19 between July 2020 and 2021 at our center. We recorded pathological, clinical, treatment characteristics, and the clinical outcome of COVID-19 infection.

RESULTS
A total 82 BC patients had COVID-19 between July 2020 and 2021. All patients were female, with a median age of 49 (43-64 years). 85% of all patients had early and 14.6% of them had advanced stage BC. COVID-19 had a mild clinical course in 73%, hospitalization was required in 27% of patients. Twenty-five patients who required hospitalization were discharged and three patients died due to COVID-19. All of the patients who died from COVID-19 had metastatic BC (p=0.002). Metastatic disease (p=0.002) and chemotherapy within 7 days of COVID-19 diagnosis (p=0.024) have been associated with increased mortality.

CONCLUSION
Majority of BC patients with COVID-19 have a mild course, patients with risk factors that increase mortality should be followed more carefully. Keywords : Advanced breast cancer; breast; cancer; chemotherapy; COVID-19, pandemic, tumor