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İstanbul Üniversitesi İstanbul Tıp Fakültesi Radyasyon Onkolojisi Anabilim Dalı, İstanbul A patient with multiple brain metastases was referred to University of İstanbul Institute of Oncology for emergency treatment of multiple brain metastases. Excisional biopsy of an inguinal lymphadenopathy showed small cell carcinoma with neuroendocrin differentiation. The patient was then received cranial irradiation and chemotherapy. Thirteen months later after initial treatment, he developed metastases of iris and choroid region of the right eye and was referred to the same clinic. After application of palliative radiotherapy to the right orbit, metastases have been regressed quickly and palliation has been obtained successfully. Keywords : Choroid neoplasms/secondary; eye diseases/etiology; iris neoplasms/pathology/secondary; uveal neoplasms/complications