TURKISH JOURNAL OF ONCOLOGY 2017 , Vol 1 , Num 1
Comparison of Dosimetric Parameters Among Preplan, Intraoperative Plan and Post-implant Plans in Low Dose Rate Prostate Brachytherapy Applications
Öznur ŞENKESEN1,Evrim TEZCANLI1,Halil KÜÇÜCÜK2,Seden KÜÇÜCÜK3,Evren Ozan GÖKSEL1,Alptekin ARIFOĞLU2,Gönül KEMIKLER3,Işık ASLAY2
1Department of Radiation Oncology, Acıbadem Mehmet Ali Aydınlar University, İstanbul-Türkiye
2Department of Radiation Oncology, Acıbadem Altunizade Hospital, İstanbul-Türkiye
3Department of Radiation Oncology, İstanbul University Oncology Institute, İstanbul-Türkiye DOI : 10.5505/tjo.2024.4369

Summary

OBJECTIVE
The aim of our study is to analyze the changes in dosimetric parameters obtained in pre-planning (PP), intraoperative planning (IOP), and post-implant dosimetry (PID).

METHODS
The study focused on the prostate as the target volume, with the rectum and urethra designated as organs at risk (OARs). Dosimetric differences between PP and IOP, PP and PID, and IOP and PID were assessed, including parameters such as prostate dose and volumes D90, pV100, pV150; urethral doses uD10, uD30, uD50; urethral volumes uV100, uV150; and rectal volumes rV100, rV150.

RESULTS
Comparing pD90 values between PP and IOP, PP and PID, and IOP and PID applications yielded p-values of 0.393, <0.001, and <0.001, respectively. For pV90 values, comparisons between PP and IOP, PP and PID, and IOP and PID showed p-values of 0.084, <0.001, and 0.001, respectively. No significant differences were observed in pD90, pV100, uD50, uV100, or rV50 when comparing PP with IOP. Similarly, no significant differences were found in uD50 or rV50 when comparing PP with PID. Comparing IOP with PID revealed no significant differences in pV150, uD30, rV50, or pV150. However, significant differences were found in all other parameters among the three applications.

CONCLUSION
The dose distribution in PP undergoes significant alterations due to edema formation and changes in the placement of OARs. Although it was determined that there were changes in PID according to the PP and IOP dose distribution, it was found to be compatible with the criteria reported in AAPM TG 137.